• The BTBR are an inbred strain of mice which

  2020-07-27

  

  The BTBR are an inbred strain of mice, which display social deficits, reduced ultrasonic vocalizations in social settings, and high levels of repetitive self-grooming (Blanchard et al., 2012). Learning and memory deficits have been reported for BTBR in fear conditioning, water maze reversal, discrim

• br Conclusion br Introduction Acute lung injury ALI and its

  2020-07-27

  

  Conclusion Introduction Acute lung injury (ALI) and its severe demonstration, acute respiratory distress syndrome (ARDS), are life-threatening clinical syndromes. The most characteristic pathological features of ALI/ARDS include increased pulmonary vascular permeability and edema, inappropriat

• The notion that a small subset of inducible cellular transcr

  2020-07-27

  

  The notion that a small subset of inducible cellular transcripts, encoding immunological important factors, is translocated across the nuclear envelope by the karyopherin CRM1 is gaining support from various recent studies. For example, experimental evidence has been provided demonstrating that the

• Of importance to the present investigation two studies Carva

  2020-07-27

  

  Of importance to the present investigation, two studies (Carvalho-Netto et al., 2007, Litvin et al., 2007) investigated the role played by CRF receptors of the dorsal periaqueductal gray (dPAG), which express both subtypes of CRF ligand sites (Merchenthaler, 1984, Swanson et al., 1983), in the regul

• Needless to say FA must enter

  2020-07-27

  

  Needless to say, FA must enter into the cell in order to be metabolized. One of the proteins involved in FA uptake is FAT/CD36, an integral membrane glycoprotein which has been found in a wide variety of cells (Abumrad et al., 1993, Coburn et al., 2000, Bonen et al., 2004). Once FA are incorporated

• CE ribotyping applied on a Czech C difficile isolate

  2020-07-27

  

  CE-ribotyping applied on a Czech C. difficile isolate collection demonstrates its high discrimination capability and the results highlight the need to use a standardised protocol as well as a standardised CE-ribotyping profile library to gain inter-laboratory comparable data on clinically and/or epi

• For the SAR optimization of the right

  2020-07-25

  

  For the SAR optimization of the right hand side, it was decided to explore the inclusion of the key carboxylic ML 141 moiety present in the original DGAT-1 inhibitors from . Analogs were constructed by the synthetic routes outlined in , . In , the methylene-oxy linker was introduced by condensatio

• Our primary research question is

  2020-07-25

  

  Our primary research question is that of the comparative efficacy of accelerated and traditional accounting programs as manifest by success on the CPA exam. We recognize that due to a number of personal and career decisions, not all of those qualified from any of our programs will attempt the CPA ex

• In rodents Wang et al Wang and Tsirka b Zhu

  2020-07-25

  

  In rodents (Wang et al., 2003, Wang and Tsirka, 2005b, Zhu et al., 2012) and humans (Wang et al., 2011), the major forms of cell death after ICH are necrosis and apoptosis. In the perihematomal region of rodents, the number of necrotic and apoptotic cells peaks at 72h post-ICH (Matsushita et al., 20

• The potent estrogen EE induced a decrease in

  2020-07-25

  

  The potent β-Tocotrienol EE2 induced a decrease in CYP2C11 activity (reduction in 2α-OH and 16α-OH testosterone) and protein at the 200 ppb dose and in this respect was similar to nonylphenol and genistein. This result agrees qualitatively with the results of Hallstrom et al. (1996) who exposed male

• br Introduction DNA dependent protein kinase DNA

  2020-07-25

  

  Introduction DNA-dependent protein kinase (DNA-PK) is a multicomponent serine/threonine protein kinase and considered a member of the phosphatidylinositol (PI) 3-kinase related kinase (PIKK family). This enzyme plays a critical role in the repair of mammalian DNA double strand breaks (DSBs) throu

• Here we uncover a highly diverse

  2020-07-25

  

  Here we uncover a highly diverse superfamily of self-replicating MGEs, dubbed pipolins, which are present in three major bacterial phyla, as well as in mitochondria, and encode divergent PolB carrying TPR1 and TPR2 subdomains. Biochemical characterization of a representative enzyme encoded by a pipo

• An AmDH is engineered by mutating two conserved

  2020-07-25

  

  An AmDH is engineered by mutating two conserved amino Tn5 DNA Library for 50 ng DNA residues in the active site of an amino acid dehydrogenase (AADH). Starting from the leucine dehydrogenase (LeuDH) from Bacillus stearothermophilus, substituting a serine and leucine at the K68 and N261 positions, r

• br Signaling of DDR receptor and its

  2020-07-25

  

  Signaling of DDR2 receptor and its regulation Being the tyrosine kinase receptor, downstream signaling of DDR2 receptor is initiated by phosphorylation of cytoplasmic tyrosine residue upon ligand binding (Type II collagen) but the authentic facts or detail information of tyrosine phosphorylation

• Poxviruses have double stranded DNA dsDNA genomes yet they r

  2020-07-25

  

  Poxviruses have double-stranded DNA (dsDNA) genomes, yet they replicate within the cytoplasm. Poxviruses that cause human disease include monkeypox virus (Reynolds et al., 2004), molluscum contagiosum virus (Hanson and Diven, 2003) and variola virus (VARV), the cause of smallpox, a disease eradicate

16375 records 823/1092 page Previous Next First page 上5页 821822823824825 下5页 Last page