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Following Duncan as a ritualized site Tyne
2020-10-10
Following Duncan (1995), as a ritualized site Tyne Cot provides an opportunity for individual tourists to conduct their own acts of remembrance (Edensor, 2000, Iles, 2006). The analysis has also shown that individual acts of writing particular words and phrases in the visitor books are socially shar
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Quantum walks can be connected to
2020-10-10
Quantum walks can be connected to extended CMV matrices as follows. If all Verblunsky coefficients with even index vanish, then the extended CMV matrix becomes which resembles the matrix representation U. One may notice, however, that in the extended CMV matrix , whereas in the quantum walk matrix
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Otherwise ES cells express high level of histone lysine
2020-10-09
Otherwise, ES SB 239063 express high level of histone lysine specific demethylase 1 (LSD1) expression. In this context, it is proposed that LSD1 inhibition may block the function of EWS-ETS proteins [70]. Furthermore, checkpoint kinase 1 (CHK1), a modulator of cell survival under the condition of im
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The synthetic route chosen for the
2020-10-09
The synthetic route chosen for the preparation of the substrates 18 is shown in Scheme 3. Commercially available 4-aminobenzyl alcohol 13 was found to be relatively unstable to storage and hence it was prepared immediately before use by reduction of the readily available and inexpensive 4-nitrobenzy
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Ultrasound is an acoustic wave with
2020-10-09
Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of
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The idea that ASB can drive compartment
2020-10-09
The idea that ASB11 can drive compartment expansion in the CNS is further supported by in vitro work in human neuronal precursors. Nerve growth factor (NGF)-induced differentiation of PC12 pheochromocytoma Potassium Canrenoate [11] and RA-induced human pluripotent teratocarcinoma carcinoma (NT2) cel
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As mentioned above there are two major pathways for
2020-10-09
As mentioned above, there are two major pathways for the DSB repair in mammalian cells, NHEJ and HR/HDR (homology-directed repair) [13], [51]. NHEJ is active throughout the cell cycle, predominately during the G0 and G1 phases and is considered the major pathway for the DSB repair in human cells [52
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br Introduction br Sphingolipid metabolism Sphingolipids
2020-10-08
Introduction Sphingolipid metabolism Sphingolipids, are fundamental constituents of all eukaryotic membranes and their metabolism is carried out by a broad array of anabolic and pkc inhibitors with ceramide as their hub (for a review, (Hannun and Obeid, 2018)). Ceramide can be formed by multip
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Electroencephalographs at onset ranged from hypsarrhythmia t
2020-10-08
Electroencephalographs at onset ranged from hypsarrhythmia to mild abnormalities but more abnormalities in background rhythms and epileptiform activity develop over time.15, 17, 19, 48, 52, 54, 55 Early mild abnormalities that sometimes precede a diffuse encephalopathy included focal delta slowing i
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pkg inhibitor br Discussion Our data demonstrate
2020-10-08
Discussion Our data demonstrate that the bicyclam AMD3100 strongly interacts with CXCR-4, whereas DS and AR177, two other compounds that also interfere with virus entry into the pkg inhibitor (and interfere with virus binding), do not. AMD3100 is a unique compound in that it interferes with the c
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Substitutions on the benzene ring
2020-10-08
Substitutions on the benzene ring of the phenyl acetic Zalcitabine synthesis moiety were evaluated to study their effect on DP and CRTH2 selectivity (). Compound has strong affinity for CRTH2, but it only has moderate affinity for DP. Small substitutions such as methoxy () and fluorine () next to
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br Materials and methods br Results br
2020-10-08
Materials and methods Results Discussion In this study, we uncovered a female-specific haplotype-MDD vulnerability association, by which a two-marker haplotype TG of rs4633-rs4680 may link to enhanced MDD risk in females. Female haplotype TG carriers were estimated to have a 9.17-fold incre
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br Acknowledgments This study was
2020-10-08
Acknowledgments This study was supported by grants from the Spanish Ministry of Economy and CompetitivenessPI10/00387, PI12/01087, PI12/01703, IPT-2011-0817-010000, and RIC Red de Investigación Cardiovascular (RIC)RD12/0042/0055. RIC is an initiative of Instituto de Salud Carlos III (ISCIII), Spa
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LEE011 Curcumin is a polyphenol extracted
2020-10-08
Curcumin is a polyphenol extracted from turmeric, which is commonly used as a spice and food-coloring agent in many cultures [9]. Curcumin possesses anti-inflammatory, antioxidant, and cancer-preventive properties [10], [11], [12]. In addition to these well-known effects, consuming curcumin may bene
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br Disclosures br Acknowledgements This work was supported
2020-10-06
Disclosures Acknowledgements This work was supported by the Natural Science Foundation of China (No. 81560587); the Fok Ying-Tong Education Foundation of China (No. 151107), the basic ability promotion project for young and middle-aged teachers in Universities in Guangxi (No. 2018KY1146) and t
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