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A memo dating to set out his specifications
2018-11-02
A memo dating to 1964 set out his specifications: In the same year, he developed the idea of marking the end of each day’s pour with marble inserts, which were alternatively flat and projecting. Although their structural role was very different, these played much the same role esthetically, in the
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Abdominal computed tomography CT Figure A
2018-11-02
Abdominal computed tomography (CT; Figure 2A) for cancer staging demonstrated right hydronephroureter, obstructed at the middle segment of the right ureter, and multiple osteoblastic bony metastases in the thoracolumbar spine. A technetium (99mTc) medronic buy atp gamma s whole-body bone scan also
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br Acknowledgments br Introduction Beh et
2018-11-02
Acknowledgments Introduction Behçet\'s disease (BD) is an inflammatory disease characterized by recurrent oral aphthous ulcers and numerous potential systemic manifestations such as genital ulcers, cycloastragenol lesions, and ocular, neurologic, vascular, articular, and gastrointestinal disea
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br Conclusion Cancer related fatigue is the most common
2018-11-02
Conclusion Cancer-related fatigue is the most common and crucial posttreatment concern among patients with cancer. It is not resolved by resting. Increasing evidence has suggested that activation of the Bleomycin Sulfate has a critical role in CRF. The outcomes of current managements for CRF are
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Treatment options for EPL tendon
2018-11-02
Treatment options for EPL tendon ruptures include direct repair, tendon grafting, and tendon transfer. Two decades ago, EIP tendon transfer was recommended as the most reliable procedure for restoring original EPL function. In case 1, direct repair or a tendon graft was not possible because the rupt
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Despite these assay limitations the results
2018-11-02
Despite these assay limitations, the results of this survey provide a snapshot of the prevalence of protozoan oocyst species of human health concern in domestic and imported leafy greens in Canada, which may assist in developing food safety guidelines, pre- and post-harvest control measures, and ris
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Chimera have been generated in the lab exclusively
2018-11-02
Chimera have been generated in the lab exclusively as interspecific chimera between mouse species (Rossant and Frels, 1980) and recently rats (review by Iannaccone and Jacob, 2009). Even within the rodent family, intergeneric chimera between mice and voles did not succeed (Mystkowska, 1975a, 1975b).
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The use of a novel Pax Venus reporter
2018-11-02
The use of a novel Pax9Venus reporter PSC line allowed the purification of PSC-derived Pax9+ AFE for molecular analysis and enabled the comparison to embryonic Pax9+ AFE. The expression of several pharyngeal endoderm transcription factors in PSC-derived Pax9+ AFE suggests that these Etonogestrel ma
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br Materials and methods br
2018-11-02
Materials and methods Results Discussion The current work showed that M3O-SKM allows for the establishment and maintenance of iPSCs in the absence of exogenous LIF. We also showed that miR-205-5p synergizes with M3O-SKM. More than 20 individuals or families of miRNAs play critical roles in
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In the following we provide
2018-11-02
In the following we provide an overview on recent applications of designer nucleases in human PSCs and on the antimalaria medication of possible targeting and selection strategies (Supplemental Table 1). Thereby, Fig. 1 highlights the key parameters which have to be considered before starting gene e
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All iPSC derived neurons demonstrated
2018-11-02
All iPSC-derived neurons demonstrated expression of functional neurotransmitter receptors, responding to glutamate/glycine, GABA and to a lower extend to acetylcholine. Interestingly, the neuronal cultures also developed synchronized spontaneous calcium oscillations, which were likely to reflect pyk
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br Experimental Procedures br Author Contributions br
2018-11-02
Experimental Procedures Author Contributions Acknowledgments Introduction The defining features of pluripotent stem nociceptin receptor (PSCs), whether they originate from germ cell tumors, from the embryo, or through cellular reprogramming, are their abilities to undergo self-renewal a
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In summary we demonstrate that GRM functions
2018-11-02
In summary, we demonstrate that GRM7 functions as a modulator of neurogenesis. We identify CREB, YAP, and CYCLIND1 as the downstream targets of GRM7. The phosphorylation of CREB at Ser133 and the expression of YAP and CyclinD1 are modulated by GRM7, thereby regulating neurogenesis. Future behavioral
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reference 2 EWS FLI a widely recognized fusion
2018-11-02
EWS-FLI1, a widely recognized fusion oncogene for Ewing sarcomas, is generated by the chromosomal translocation of t(11;22) (q24;q12), which consists of the N-terminal transactivator domain of the EWS gene and the C-terminal ETS DNA binding domain of the FLI1 gene. The resulting EWS-FLI1 fusion prot
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br Experimental Procedures See also Supplemental Experimenta
2018-11-02
Experimental Procedures See also Supplemental Experimental Procedures. Author Contributions Acknowledgments We thank Dr. Yun Deng for providing Tg (myl7:EGFP) zebrafish, Dr. Niels C. Bols and Dr. Peng Hu for their technical support with zebrafish. This work was supported by the National Na
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