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According to the biomechanics of tree
2018-11-06
According to the biomechanics of tree׳s shape, trees make compromises. Longer a branch, the more likely it is to break under the pull of gravitation. Therefore, the tree has to compromise its shape that can expose as many Ezetimibe manufacturer as possible, but by limiting the growth of a branch to
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prostanoid receptors br Acknowledgments We acknowledge the G
2018-11-06
Acknowledgments We acknowledge the Graduate Institute of Biomedical Engineering of National Central University, the Landseed Hospital (Grant No: LS-S-2008-01), and the National Science Council (Grant No: NSC96-2221-E008-105MY2), Taiwan, for their support of this study. Introduction Case rep
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The technique of transaxillary subfascial dissection has bee
2018-11-06
The technique of transaxillary subfascial dissection has been used for esthetic augmentation mammaplasty. Because the cephalic portion of the fascia of the pectoralis major is more defined and resistant than its inferior portion, this cephalic undermining for a neck lesion can be done easily to keep
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The antigens are taken up by several antigen presenting cell
2018-11-06
The gamma secretase inhibitor are taken up by several antigen-presenting cells (APCs) where they are processed for presentation to T cells in the PPs. The T cells are activated upon antigen presentation, and then differentiate and mature in the germinal centers of the follicles. They migrate via eff
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br Self organized pattern formation
2018-11-06
Self-organized pattern formation at the ‘edge of chaos’ Self-organization is a key concept in theoretical physics that buy Tunicamycin refers to a state far from thermodynamic equilibrium that arises when microscopic fluctuations are too great for a system to contain (Ball, 2001; Chaisson, 2004;
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The neuroprotective effect of hypoxic preconditioning in the
2018-11-06
The neuroprotective effect of hypoxic preconditioning in the azidothymidine has been studied by several groups who found evidence for the involvement of HIF-1α and its downstream targets and/or Epo (He et al., 2008) (Liu et al., 2005; Theus et al., 2008) (Prass et al., 2003) (Bernaudin et al., 2002
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Like many of the established animal based
2018-11-06
Like many of the established animal based ex vivo cardiac safety pharmacology models (Langendorf, Purkinje fiber, ventricular wedge) the present assay is based on measuring the net cellular electrical activity (monophasic atp gamma s or field potential in case of the MEA) instead of a single isolat
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Similar to our observation that
2018-11-06
Similar to our observation that Nanog−/− iPSCs could give rise to chimeric animals, Nanog null ESCs have been shown to contribute to the three germ layers (Chambers et al., 2007). However, in the case of ESC chimeras, Nanog−/− GFP+ tachykinin receptor were not detected in the germline after E12.5. B
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Fibroblasts can be directly reprogrammed into neurons Vierbu
2018-11-06
Fibroblasts can be directly reprogrammed into neurons (Vierbuchen et al., 2010), cardiomyocytes (Ieda et al., 2010), and NSCs (Han et al., 2012) using tissue-specific combinations of transcription factors. However, the pluripotent reprogramming cocktail of Oct4, Sox2, Klf4, and Myc can also convert
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The following are the supplementary data related to
2018-11-06
The following are the supplementary data related to this article. Introduction Materials and methods Results Discussion Within the human body, three mechanisms of blood vessel formation can be distinguished, namely vasculogenesis, arteriogenesis and angiogenesis. In particular angiogene
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Before the Hippo pathway was
2018-11-06
Before the Hippo pathway was delineated in Drosophila, several crucial components of the pathway had already been cloned in mammals (Tapon et al., 2002; Xiao et al., 1991; Sudol, 1994; Creasy and Chernoff, 1995; Tao et al., 1999). The functions of these crucial Hippo pathway components have been wel
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Molecular karyotyping identified a novel
2018-11-06
Molecular karyotyping identified a novel 2.4Mb gain on chromosome 5p14.3 and a gain on chromosome 12p11.21, which was also found in KCL040. The gain on chromosome 5p14.3 containing a single gene, CDH18 (Cadherin-18), was also present in one of two sibling cell lines, KCL032, but not in KCL034, a th
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TSA a HDAC inhibitor has a differential
2018-11-06
TSA, a HDAC inhibitor, has a differential affinity to bind various HDAC complexes (Bantscheff et al., 2011). In the present study, ChIP analysis revealed that HDAC2 and HDAC3 are bound with higher affinity to the Cyclin B1 promoter in BMSCs and the Cyclin D2 promoter in HSPCs, which inhibits the exp
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br Materials and methods br Author disclosure statement br A
2018-11-06
Materials and methods Author disclosure statement Acknowledgments This study was supported by fund from National Medical Research Council (NMRC) of Singapore, the Translational Clinical Research (TCR) award (NMRC/TCR/013-NNI/2014) and STaR award (NMRC/STaR/014/2013). We thank Ms. Fiona Seti
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We previously showed that huntingtin HTT the protein mutated
2018-11-06
We previously showed that huntingtin (HTT), the protein mutated in Huntington’s disease (HD), is required in murine neuronal progenitors for appropriate spindle orientation and for cell fate determination (Godin et al., 2010). Yet, the mechanisms underlying HTT function during spindle orientation re
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