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In primary diagnosis IKZF status was not taken into
2019-04-19

In primary diagnosis IKZF1 status was not taken into account for risk group stratification. According to protocol ALL-MB-2002 regulations, risk was underestimated and patient was assigned to the SRG. Prognostic value of IKZF1 alterations in ALL, especially BCR-ABL1 negative ALL, is still debated [19
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br Conclusions br Conflict of
2019-04-19

Conclusions Conflict of interest Introduction Arrhythmogenic right ventricular cardiomyopathy (ARVC), previously called arrhythmogenic right ventricular dysplasia (ARVD), is an inherited disease characterized by right ventricular degeneration and ventricular arrhythmias. ARVC is one of the
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During a mean of months of follow up
2019-04-19

During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll
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The results of our initial cross sectional
2019-04-19

The results of our initial cross-sectional analyses assessing the clinical characteristics of the patients participating in ASSAF-K are shown in Table 1. As compared with the “Fushimi AF Registry,” considered a representative Japanese AF registry with an initial registration of 3183 patients [28], t
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br La difusi n en
2019-04-19

La difusión en España de la Música práctica, impresa en Boloña en 1482 y escrita originalmente en latín, no sólo es innegable, sino decisiva ikk pathway lo largo del siglo xvi. Francisco Salinas es un firme defensor de las teorías de Ramos Pareja y, sobre todo, toma su partido en relación con las
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Y sin embargo de esos pueblos presuntamente reaccionarios
2019-04-19

Y sin embargo, de esos pueblos presuntamente reaccionarios por naturaleza provienen muchos de los más importantes escritores de La Tribune des Peuples. Los escritos de esos colaboradores tienen como fin afirmar la historicidad de esos pueblos y la continuidad de sus luchas. Los radicales de La Tribu
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The Sustainable Development Goals can be
2019-04-18

The Sustainable Development Goals can be achieved through environmental prevention of diseases without an additional burden on resources. The WHO avoidable early environmental exposures initiative emphasises that the unrecognised health risks are most damaging to the human population. An absence of
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One of the unheralded developments in global
2019-04-18

One of the unheralded developments in global health is the welcome increase in the number of older people (ie, aged 60 or 65 years and older) in low-income and middle-income countries. In parallel with the gains from this longevity dividend, ageing presents particular challenges to health services.
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br Methods br Results br Discussion
2019-04-18

Methods Results Discussion ICC represents an aggressive malignancy arising from the intrahepatic biliary tree. Recent years have seen a dramatic increase in the incidence of ICC, making it the second most common primary liver cancer. Prognosis of ICC remains poor, with 5-year OS rates rangi
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One study reported the role of the Purkinje system
2019-04-18

One study reported the role of the Purkinje system with respect to the relationship between the septum and HCM-related VT. Santangeli et al. reported that patients with HCM also often have His-Purkinje conduction-related septal abnormalities, and bundle branch block often develops as part of the nat
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Both breast cancer and MM cause osteolytic lesions
2019-04-18

Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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M s all de la tiran a
2019-04-18

Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto GDC-0994 la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción poética de Neruda: la
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M s all del justificado resentimiento de los tamaulipecos es
2019-04-17

Más allá del justificado resentimiento de los tamaulipecos, es el escritor Mauricio Magdaleno en su antología Escritores extranjeros en la Revolución (1979), quien ofrece el juicio más interesante sobre la novela, en su breve presentación del autor norteamericano. A diferencia de Gunn, para quien Ta
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br Basis and methodology of DCE MRI DCE
2019-04-17

Basis and methodology of DCE-MRI DCE-MRI images are performed by using injecting low-molecular-weight gadolinium chelated contrast agent with a constant, stable rate. The contrast agent is carried by blood flow into the tissue, causing increased signal intensity (SI) of the T1-weighted images due
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mg115 cost Residing in West Germany also decreased BIS persi
2019-04-17

Residing in West Germany also decreased BIS persistence. In 2015, Jacob et al. demonstrated in 4,915 BC women that the treatment discontinuation rate is higher in West Germany than in East Germany [1]. Finally, our study returned one outcome that requires careful discussion: we found that private he
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