• Preference for injectable therapy over oral therapy

  2019-05-17

  

  Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne

• The finding that baseline VEGF in the Zamboney study was

  2019-05-17

  

  The finding that baseline VEGF in the Zamboney study was not associated with clinical outcomes are in chemokine receptor to other published studies. VEGF was previously shown to be associated with better treatment outcomes in metastatic breast cancer patients treated with bevacizumab [26,31]. This d

• br Bone half life based dosing As zoledronic acid has

  2019-05-17

  

  Bone half-life based dosing As zoledronic natriuretic peptide receptor has been shown to have anti-tumor efficacy in both the pre-clinical and clinical settings using the conventional regimen (zoledronic acid 4mg infusion 4 weekly), some studies were designed to explore the anti-tumor effects of

• on October is an annual opportunity to

  2019-05-17

  

  , on October 24, is an annual opportunity to revitalise attention and efforts towards the global eradication of this now rare but still fatal and devastatingly disabling infectious disease. 2014 has not felt like a good year for infectious disease control, yet just 3 months from now, a major date in

• br Material and Methods br

  2019-05-16

  

  Material and Methods Results Discussion Radiofrequency ablation has a long history of use. It has been used especially in the neurosurgical field [8,9]. Rosenthal described the first ablations in bone 20 years ago [5]. Technically the radiofrequency generator forms an electric current leadi

• El libro de William Crawford publicado

  2019-05-16

  

  El libro de William Crawford publicado en 1944, traducido en 1966, y las obras de Leopoldo Zea de 1949 y de 1965, aunque de muy distinto carácter y alcance, suscitaron primero un artículo de Oscar Kubitz en 1960, después un ensayo de Salomon Lipp en 1975, y, finalmente, otro artículo de frank Spindl

• Ante la necesidad de unas reglas

  2019-05-16

  

  Ante la necesidad de unas reglas o códigos propyl partir de los cuales evaluar la producción de los decadentistas, el autor del artículo se lamenta de su inexistencia: “¿Dónde está el código de los decadentistas? No le tienen porque en vez de reglas lo que ellos practican es la violación caprichosa

• br Antimicrobial drugs are the most counterfeit

  2019-05-16

  

  Antimicrobial drugs are the most counterfeit or substandard drugs worldwide. The pharmacopoeial quality of these drugs in China is of special concern because China is the second producer, after India, of most counterfeit or substandard drugs in the global market. The antimicrobials circulating in

• br Case report A years

  2019-05-16

  

  Case report A 51-years-old man visited our hospital presenting with a palpable mass over the right inguinal area which had persisted for 3 months. This lesion was approximately 3–4 cm, firm and had progressively enlarged. Laboratory data showed no remarkable anomaly except elevated lactate dehydr

• Curative treatments which include surgical

  2019-05-16

  

  Curative treatments, which include surgical resection, percutaneous ablation and liver transplantation, were considered as the optimal treatment for patients with very early/early stage HCC by BCLC criteria. Furthermore, advances in liver surgery make the resection of large and/or multifocal HCC pos

• roscovitine br Material and methods The study

  2019-05-16

  

  Material and methods The study population was selected from the National Cancer Institute’s SEER database. The SEER database collects data from 18 geographic registries, covering approximately 28% of the U.S. population [17]. The SEER⁎Stat software (Version 8.0.4; NCI; Bethesda, MD) was used to i

• Along the same line there is no information

  2019-05-16

  

  Along the same line, there is no information in the literature on the optimal RT schedule in such cases. Doses ranging from 40 to 45Gy should be adequate and we chose to give 2Gy daily. This schedule was based on clinical and radiological evolution of the patient. RT limits natural evolution of the

• br Erythropoietin and the HSC

  2019-05-16

  

  Erythropoietin and the HSC niche Many molecules produced both locally and systemically, including erythropoietin (Epo) and adrenergic catecholamines, also appear to affect HSC niche and metastatic lesions in the bone marrow. EPO is a hematopoietic hormone produced predominantly in the kidneys in

• br Material and methods br Results

  2019-05-16

  

  Material and methods Results Thirty-one patients were enrolled consecutively, in this randomized study, between January 2010 and March 2012. The mean age was 65.5±13.7 years. The proportion of patients with primary prevention indication was 25.8% and ischemic cardiomyopathy was 29.0%. All repo

• Ethiopia is faced with challenging circumstances It is a low

  2019-05-15

  

  Ethiopia is faced with challenging circumstances. It is a low-income country, with a gross domestic product estimated by the International Monetary Fund at US$570 per person in 2014, and 66% of the purchase SB 203580 hydrochloride living on less than US$2 per day in 2011—rates that are even lower t

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